How Hepatitis C is Diagnosed

Health care provider taking blood from man's arm.
To test for hepatitis C, blood is taken and sent to a lab. It may take a few weeks to get your test results.

To find out if you are infected with the hepatitis C virus, your healthcare provider will ask questions about your health. He or she may also try to figure out how long you have been infected with hepatitis C. This may involve questions that seem personal. It’s important to answer honestly. You should also mention any symptoms that concern you. To test for hepatitis C, a sample of your blood is taken. The blood is sent to a lab. It may take a few weeks to get your test results. You may have a physical exam and other tests help check for liver damage.

Getting tested

The CDC advises that all people born between 1945 and 1965 get tested for hepatitis C. Blood tests look for substances in your blood that are linked to hepatitis C. These include:

  • ALT. This is a liver enzyme. Blood may have more ALT if the liver has been damaged.

  • Anti-HCV. The body tries to fight hepatitis C by making an antibody called anti-HCV. This substance is found in the blood and means you have been exposed to hepatitis C.

  • Genotype. There are 6 hepatitis C genotypes. A blood test can show which genotype you have. This will affect the type of treatment.

  • HCV RNA. Some tests can show pieces of hepatitis C in infected blood. This can confirm that you are currently infected.

Looking for liver damage

During an exam, your healthcare provider may feel your abdomen. This is to see if your liver is swollen or painful. Tests may also be done to check your liver for damage. These tests include:

  • CT scan. This is a series of X-rays that shows a detailed picture of the liver by making cross-sectional images.

  • Fibrosis panel. This blood test can help show how severe the liver disease is.

  • Liver biopsy. A needle is used to take a small sample of tissue from the liver. The sample is then viewed under a microscope to look for inflammation and the amount of scar tissue.

  • MRI scan. This is a scan where strong magnetic fields and radio waves make images of the liver and blood vessels.

  • Ultrasound. This test uses painless sound waves to create a picture of the liver. It can roughly stage your liver disease. Your spleen size and portal vein size should be measured with each exam. The exam should take at least 20 minutes to make sure you have the correct number of images of the liver.

Checking for other infections

Hepatitis C infection can be more dangerous if you also have certain other viruses. Your healthcare provider may test you for HIV and other types of hepatitis, such as types A and B. If you have not had hepatitis A or B, you may be given vaccines to protect you from getting them in the future.

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