Sodium Picosulfate, Magnesium Oxide, Citric Acid, Anhydrous Oral solution

What is this medicine?

Sodium picosulfate; magnesium oxide; citric acid, anhydrous (SOE dee um PI koe SUL fate; mag NEE zee um OX ide; SIT rik AS id an HYE drus) is a laxative. It is used to clean out the bowel before a colonoscopy.

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Clenpiq is ready to drink. Each dose of Prepopik must be mixed with 150 mL (5 ounces) of cold water before taking the dose. Your doctor will tell you what time to start this medicine. Take exactly as directed. You will need to drink additional clear fluids after each dose. Do not skip a dose or stop your medicine early. Take other oral medicines 2 hours before or 6 hours after this medicine to avoid decreasing their absorption.

You will need to follow a special diet before your procedure. Talk to your doctor. You may drink clear liquids while taking this medicine and up until 2 hours before colonoscopy.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 9 years of age for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • confusion

  • dizziness

  • fast, irregular heartbeat

  • feeling faint or lightheaded, falls

  • seizures

  • trouble passing urine or change in the amount of urine

  • vomiting

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • bloating

  • diarrhea

  • mild headache

  • nausea

  • stomach pain

  • upset stomach

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • alcohol

  • other laxatives

This medicine may also interact with the following medications:

  • certain antibiotics, like ciprofloxacin, levofloxacin or tetracycline

  • certain medicines for blood pressure, heart disease, irregular heart beat

  • chlorpromazine

  • certain medicines for depression, anxiety, or psychotic disorders

  • certain medicines for diabetes

  • certain medicines for seizures

  • diuretics

  • iron supplements

  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen

  • penicillamine

  • steroid medicines like prednisone or cortisone

  • theophylline or aminophylline

  • tramadol

What if I miss a dose?

This does not apply. This medicine is not for regular use.

Where should I keep my medicine?

Keep out of the reach of children. Do not share this medicine with anyone.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not refrigerate. Do not freeze. Do not add ice to the solution. Throw away any unused medicine after the day of the colonoscopy. Do not store the solution for later use.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • dehydration

  • difficulty swallowing

  • heart disease

  • high or low levels of calcium, magnesium, potassium, or sodium in the blood

  • history of irregular heartbeat

  • kidney disease

  • seizures

  • stomach or intestine problems

  • an unusual or allergic reaction to sodium picosulfate; magnesium oxide; anhydrous citric acid, other medicines, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

You will need to follow a special diet before your procedure. Talk to your healthcare professional.

Talk to your healthcare professional if you are not able to complete the regimen as prescribed.

Do not use with any other laxatives. Drink clear fluids as directed to prevent dehydration. See your healthcare professional right away if you do not have a bowel movement after using this medicine.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2021 Elsevier
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